园友接待 规章 你问我答 新手资源 宣传 活动 资源超市 检索 代理 国外 精品 VIP 初级 中级 学术嘉宾 群英会 版主 区版 管委 邀请朋友 (有奖!)

科研经验 投稿 基金 课件 科软 会议 教学 精品馆 互助 硕博 标准求助|共享 书籍 S 考研 考博 英语 资格 公务员 考试精品 工作 留学 交友

数学 物理 化学化工 生命 地学 环境 机械 力学 能源 材料 土建 水利 信息 电力 电子 信息工程 理综 药学 医学 外科 内科 妇儿五官 公卫 医综

文史哲 外语 法学 经济 年鉴 报告 管理与教育 文学原创 零点家园 影音 美图 脑力 体育 健康生活 时尚 心理 美食 医护 电脑网络 百宝箱

返回列表 回复 发帖

[前沿] [生科综合] 海洛因可能能够治疗海洛因瘾症

[前沿] [生科综合] 海洛因可能能够治疗海洛因瘾症

前沿

原创与否 -
海洛因可能能够治疗海洛因瘾症
波士顿(路透社报道)-加拿大研究者在星期三宣称,注射海洛因有效活性成分治疗海洛因成瘾要比美沙酮有效的多,可以使他们不再使用违禁药品和给社会制造麻烦。
但研究者们同时也提醒说注射剂量过大会存在危险并可能使瘾加重,因此注射海洛因应该仅在治疗范围内允许。
“最适用药规范所推荐的美沙酮仍然应该是大多数病人的首选。”英国哥伦比亚大学的欧尼亚奥维多乔克斯和他的同事在新英格兰医疗杂志上写道。
但当美沙酮不起作用时,他们说,给病人注射海洛因有效成分二乙醯吗啡似乎是一个有效的选择。目前美沙酮治疗对15%-25%寻求治疗的病人不起作用。
奥维多乔克斯和他的同事研究了蒙特利尔市和范库弗峰市的226名海洛因瘾症患者。他们发现使用美沙酮治疗患者只有54%一年后仍使用美沙酮治疗。
但使用二乙醯吗啡的患者88%一年仍使用二乙醯吗啡治疗,且使用二乙醯吗啡的患者67%禁绝了违法药品,而使用美沙酮的患者仅有48%。
所有使用二乙醯吗啡的患者到每次诊所诊治时至少花45分钟时间来检查副作用。有人甚至一天去三次诊所。
四分之三的海洛因瘾症患者说他们在用药前一个月有过与药品无关的不合规定的行为,使用美沙酮后这种行为降到了5.4%,而使用二乙醯吗啡后这种行为下降到了0.9%
你只要一想到使那些成瘾者远离街道,不再犯罪,不再钻入深巷而是让他们进入诊所接受医生护士和顾问的治疗,一些人就会说,“啊哈,我明白了”。他们就已经意识到了这个发现的实用性。参与这项研究的英哥伦比亚大学的马丁斯科特博士在电话采访中说.
这种治疗方式一年花费少于10000美元。我们知道不接受治疗的成瘾患者,社会每年对他们的花费是50000美元,这些花费包括紧急情况处理室,医生,法庭,警察和监禁等等。他说。
目前北美洲约有100万海洛因瘾者。
这项研究也期望能对欧洲也会起到一些作用。在那里类似的试验也产生了很明显的对比结果。
瑞士十年前就已经把海洛因当成了药方。
在欧洲,对于那些没有其他方法可以治疗的和那些不能美沙酮无效的病人,海洛因已经被认为是治疗的最佳方式。它可以使使用者仍然与药物保持联系。伦敦大学的维吉尼亚波瑞德在解说词中写道。


http://www.reuters.com/article/healthNews/idUSTRE57I65420090820

Treating heroin addiction with heroin seems viable

BOSTON (Reuters) - Injections of the active ingredient of heroin work far better than oral methadone for keeping addicts in treatment, away from illegal drugs and out of trouble, Canadian researchers reported on Wednesday.

But the researchers cautioned that the treatment carries a risk of overdose and seizures, so the injections should only be done in a medical setting.

"Methadone, provided according to best-practice guidelines, should remain the treatment of choice for the majority of patients," Eugenia Oviedo-Joekes of the University of British Columbia and colleagues wrote in the New England Journal of Medicine.

But when that does not work, they said, giving heroin's active ingredient, diacetylmorphine, appears to be an effective alternative. Methadone treatment fails in 15 to 25 percent who seek care.

Oviedo-Joekes and colleagues studied 226 addicts in Montreal and Vancouver. Only 54 percent of those who got methadone stayed in treatment for a year, they found.

But 88 percent of those who got diacetylmorphine shots did. And those who got diacetylmorphine cut back on illicit drugs by 67 percent, compared to 48 percent who got methadone.

All the addicts who received diacetylmorphine spent at least 45 minutes per visit in the clinic to check for side effects. Some were there three times a day.

While three quarters of the addicts said they had engaged in non-drug-related illegal activities in the previous month, the rate dropped to 5.4 percent with methadone treatment and 0.9 percent for the diacetylmorphine recipients.

"Once you open your mind to the idea of getting people off the streets, out of crime, out of the back alleys and into clinics where they're going to be treated by doctors and nurses and counselors, some people will say, 'Ah ha! I get it now.' They begin to see the pragmatic side of the argument," Dr. Martin Schechter of the University of British Columbia, who worked on the study, said in a telephone interview.

The cost of heroin treatment is less than $10,000 per year. "We know a person who is out of treatment, their cost to society is over $50,000 a year, and that includes emergency room visits, doctors, courts, police and jail and so on," he said.

North America has about a million heroin addicts.

The results are expected to have little impact in Europe, where similar tests have produced comparable results.

Switzerland has been prescribing heroin for a decade.

"The prescription of heroin is now recognized in some European countries as the optimal treatment for patients for whom options are running out and in whom methadone maintenance has not worked, and it keeps the user in contact with drug services," Virginia Berridge of the University of London wrote in a commentary.

(Editing by Maggie Fox and Todd Eastham)



春雪轻盈地飞舞着,在春风中轻轻吟唱一首绵绵的情歌。北京白癜风医院,歌声缠缠绵绵、丝丝缕缕,如柔美悦耳的钢琴曲,北京白癜风,在寂寥的北疆原野上,银子一样流淌着。雪花轻歌慢舞地,在春风温暖的怀抱里撒娇,北京白癜风医院,像似一群淘气的幼童,欢呼雀跃地在大地上嬉戏。fejruihgdfjghd


返回列表

零点花园属于纯学术、非经营性专业网站。

大家出于学习和科研目的进行交流讨论,如有涉侵犯著作权人的版权等信息,请及时来信告知,我们将在3个工作日内做出相应的处理,并给予相应的答复,谢谢。

辽宁网警

辽宁网警